Publications

Peer Reviewed Publications (reverse chronological order):

 

  1. Zhang, M. M., Bahal, R., Rasmussen, T. P., Manautou, J. E., and Zhong, X.B. (2021) The growth of siRNA-based therapeutics: updated clinical studies. Biochemical Pharmacology (in press) PMID: 33513339

 

  1. Prabhakar, B., Lee, S.W., Bochanis, A., Manautou, J., and Rasmussen, TP. (2021) lnc-RHL, a novel long noncoding RNA required for the differentiation and survival of hepatocytes from human bipotent progenitor cells Cell Proliferation DOI: 10.1111/cpr.12978 PMID: 33393114

 

  1. Rasmussen, T. (2020) Reviewed Work: Epigenetics, Nuclear Organization and Gene Function: with implications of epigenetic regulation and genetic architecture for human development and health. John C Luchessi, author (2019). Quarterly Review of Biology, University of Chicago Press. 

 

  1. McCabe, E.M., and Rasmussen, TP. (2020) lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions. Seminars in Cancer Biology, doi: 10.1016/j.semcancer.2020.12.012. PMID: 33346133

 

  1. 60. Malik, S., Gupta, A, Zhong, X, Rasmussen, T, Manautou, J., and Bahal, R. (2020) Emerging Therapeutic Modalities against COVID-19. Pharmaceuticals 13 (8), 188. PMID: 32784499

 

  1. Singh, S., Bahal, R., and Rasmussen, TP. (2020) Evidence that miR-152-3p is a positive regulator of SETDB1-mediated H3K9 histone methylation and serves as a toggle between histone and DNA methylation.Experimental Cell Research 395 (2): https://doi.org/10.1016/j.yexcr.2020.112216 PMID: 32768498

 

  1. Lee, S.W., Bochanis, A., and Rasmussen TP (2020). Pluripotent cells for the assessment of chemically-induced teratogenesis and developmental toxicology: in Engineering Strategies for Regenerative Medicine (Elsevier) (London, U.K.).

 

  1. Chen L. Manautou JE, Rasmussen TP, and Zhong XB (2019) Development of precision medicine based on inter-individual variability of BCRP/ABCG2. Acta Pharmaceutica Sinica B, (in press), APSB-2018-831. PMID: 31384528

 

  1. Rasmussen, T. (2019) Parallels between artificial reprogramming and the biogenesis of cancer stem cells: involvement of lncRNAs. Seminars in Cancer Biology 57: 36-44. PMID: 30273656

 

  1. Heinrich, A, Xhong, X.B, and Rasmussen, T. (2018) Variability in expression of the human MDR1 drug-efflux transporter and genetic variation of the ABCB1 gene: implications for drug-resistant epilepsy. Current Opinion in Toxicology 11-12: 35-42.

         PMID:  31602418

 

  1. Rasmussen, T. (2018) Stem Cells in Birth Defects Research and Developmental Toxicology. Hoboken, NJ.: John Wiley and Sons, Rasmussen ed.

 

  1. Prabhakar, B., Lee, S., and Rasmussen, T.P. (2018) The basics of stem cells and their utility as platforms to model teratogen action and human developmental and degenerative disorders: in Stem Cells in Birth Defects Research and Developmental Toxicology. John Wiley and Sons, Inc. Rasmussen ed. (Hoboken, USA 2018).

 

  1. Bau, Y., Ma, X., Rasmussen, T.P., and Zhong, X.B. (2018) Genetic variations associated with anti-tuberculosis drug-induced liver injury. Current Pharmacology Reports 4 (3): 171-181. PMID: 30464886

 

  1. Flamier, A., Singh, S., and Rasmussen, T.P. (2018) Use of human embryoid bodies for teratology. Current Protocols in Toxicology, 75, 13.13.1–13.13.14. doi: 10.1002/cptx.38 PMID: 29512128

 

  1. Prabhakar, B. and Rasmussen, TP. (2017) Exploiting long noncoding RNAs as pharmacological targets to modulate epigenetic disease. Yale Journal of Biology and Medicine. 90(1):73-86. PMID: 28356895

 

  1. Flamier, A., Singh, S. and Rasmussen, TP. (2017) A standardized human embryoid body platform for the detection and analysis of teratogens. PLoS One 12(2): e0171101. PMID: 28182681

 

  1. Rasmussen, T. (2016) Reviewed Work: Stem Cells in Development and Disease. Michael Rendl, ed.Quarterly Review of Biology, University of Chicago Press. 

 

  1. Rasmussen, T.P. (2016) Genomic medicine and lipid metabolism: LDL targets and stem cell research approaches. In: Translational Cardiometabolic Genomic Medicine Elsevier, Oquendo-Rodriguez ed. (London, 2016).

 

  1. Rasmussen, T. (2015) Reviewed Work: Current Topics in Developmental Biology: Epigenetics and Development. Edith Heard, ed. Quarterly Review of Biology, University of Chicago Press. 

 

  1. Rasmussen, T. (2015) Reviewed Work: Epigenetic Regulation and Epigenomics: Advances in Molecular Biology and Medicine Robert A. Meyers, ed. Volumes 1 and 2. Quarterly Review of Biology, University of Chicago Press. 

 

  1. Rasmussen, T. (2015) The epigenetics of nuclear reprogramming. Epigenetics: Current Research and Emerging Trends.: Caister Academic Press, Chadwick ed. (Poole, UK: 2015).

 

  1. Flamier, A., and Rasmussen, T. (2014) Using human pluripotent cells to detect teratogens and study teratogenic mechanisms. Birth Defects Research, Part A, Clinical and Molecular Teratology.  (100): 403. 

 

  1. Bharadwaj, R., Peter, C.J., Jiang, Y., Roussos, P., Vogel-Ciernia, A., Shen, E., Mitchell, A., Mao, W., Whittle, C., Dincer, A, Jakovcevski, M., Pothula, V., Rasmussen, T. P., Giakoumaki, S.G., Bitsios, P., Sherif, A., Gardner, P.D., Ernst, P., Ghose, S., Sklar, P., Haroutunian, V., Tamminga, C., Myers, R.H., Futai, K., Wood, M.A., and Akbarian S. (2014) Conserved Higher Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition. Neuron 84: 997-1008. PMID: 23864674

 

  1. Rudraiah, S., Rohrer, P., Gurevich, I., Goedken, M., Rasmussen, T., Hines, R., Manautou, J. (2014) Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes Toxicological Sciences 141(1): 263-277. PMID: 24973094

 

  1. Krueger, W., Boelsterli, U.A. and Rasmussen T.P. (2014) Stem cell strategies to evaluate idiosyncratic drug-induced liver injury. Journal of Clinical and Translational Hepatology 2: 143-152. PMID: 26355943

 

  1. Rasmussen T.P. (2014) The epigenetics of early development; inferences from stem cells. Molecular Reproduction and Development (2):194-201. PMID: 24150934

 

  1. Mitchell, AC. M., Bharadwaj, R., Whittle, C., Krueger, W., Hurd Y., Mirnics, K., Rasmussen, T., and Akbarian, S. (2014) The genome in three dimensions: A new frontier in human brain research.  Biological Psychiatry75 (12): 961-969. PMID: 23958183

 

  1. Lee KK, Fujimoto K, Zhang C, Schwall CT, Alder NN, Pinkert CA, Krueger W, Rasmussen T, Boelsterli UA. (2013) Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatoctyes. Free Radical Biology and Medicine. 65: 584-594. PMID: 23911619

 

  1. Bharadwaj, R., Jiang, Y., Mao, W., Jakovcevski, M., Dincer, A., Krueger, W., Garbett, K., Whittle, C., Tushir, J.S., Liu J., Sequeira, A., Vawter, M., Gardner, P., Casaccia, P., Rasmussen, T.P., Bunney, W.E., Jr., Mirnics, K., Futai, K., and Akbarian, S (2013) Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia Journal of Neuroscience (33) 29: 11839-11851. PMID: 23864674

 

  1. Krueger, W., Tanasijevic, B., Barber, V., Flamier, A., Gu, X. Manautou, J., and Rasmussen, T.P. (2013) Cholesterol-secreting and statin-responsive hepatocytes from human ES and iPS cells to model hepatic involvement in cardiovascular health. PLoS ONE 8(7): e67296. doi:10.1371/journal.pone.0067296 PMID: 23874411

 

  1. Wei, S., Zan, L., Hausman, G.J., Rasmussen, T.P., Bergen, W.G., and M.V. Dodson (2013) Dedifferentiated adipocyte-derived progeny cells (DFAT cells); Potential stem cells of adipose tissue.  Adipocyte 2 (3): 122-127. PMID: 23991357

 

  1. Krueger, W.H, Tanasijevic, B.T., Norris C., Tian, X.C. and Rasmussen, T.P. (2013) Oct4 Promoter activity in stem cells obtained through somatic reprogramming. Cellular Reprogramming 15 (2):151-158. PMID: 23550731

 

  1. Dai,B., Giardina, C. and Rasmussen, T.P. (2013) Quantitation of Nucleosome Acetylation and other Histone Post-Translational Modifications Using Microscale NU-ELISA. Methods in Molecular Biology 981: 167-176. PMID: 23381861

 

  1. Tanasijevic, B. and Rasmussen, T.P. (2011) X Chromosome Inactivation and Differentiation Occur Readily in ES Cells Doubly-Deficient for MacroH2A1 and MacroH2A2. PLoS ONE 6(6): e21512. doi:10.1371/journal.pone.0021512. PMID: 21738686

 

  1. Dai, B., Dahmani, F., Cichocki, J.A., Swanson, L.C., Rasmussen, T.P. (2011). Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA. Journal of Visualized Experiments 26;(50). pii: 2593. doi: 10.3791/2593 PMID: 21540828

 

  1. Krueger, W., Swanson, L., Tanasijevic, B., Rasmussen, T.P. (2011) Natural and Artificial Routes to Pluripotency. International Journal of Developmental Biology 54: 1545-1564. PMID: 21404178

 

  1. Dodson, M.V., Hausman, G. J., Guan, L.L., Du, M., Rasmussen, T.P., Poulos S.P., Mir, P., Bergen W.G., Fernyhough, M.E., McFarland, D.C, Rhoads , R.P., Soret, B., Reecy, J.M., Velleman, S.G., and Jiang, Z. (2010) Lipid metabolism, adipocyte depot physiology and utilization of meat animals as experimental models for metabolic research. International Journal of Biological Sciences 6(7): 691-699. PMID: 21103072

 

  1. Dodson, M.V., Hausman, G.J., Guan, L.L., Du, M., Rasmussen, T.P., Poulos, S.P., Mir, P., Bergen, W.G., Fernyhough, M.E., McFarland, D.C., Rhoads, R.P., Soret, B., Reecy, J.M., Velleman, S.G., Jiang, Z. (2010) Skeletal muscle stem cells from animals I. Basic cell biology. International Journal of Biological Sciences 6(5): 465-474. PMID: 20827399

 

  1. Rasmussen, T.P., and Corry, G.N. (2010) Epigenetic pre-patterning and dynamics during initial stages of mammalian preimplantation development. Journal of Cellular Physiology 225: 333-336. PMID: 20607796

 

  1. Barry, E.R., Corry, G.N., Rasmussen, T.P. (2010) Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development. Expert Opinion on Therapeutic Targets 14(4): 405-418. PMID: 20230194

 

  1. Chang,C.C., Gao, S., Sung, L.Y., Corry,G.N., Ma, Y.H., Nagy, Z.P., Tian, X.C., Rasmussen, T.P. (2010) Rapid Elimination of the Histone Variant MacroH2A from Somatic Cell Heterochromatin after Nuclear Transfer. Cellular Reprogramming 12(1):43-53. PMID: 20132012

 

  1. Corry, G.N., Tanasijevic, B., Barry, E.R., Krueger, W., Rasmussen, T.P. (2009) Epigenetic regulatory mechanisms during preimplantation development. Birth Defects Research, Part C: Embryo Today. 87(4):297-313. PMID:19960551

 

  1. Tanasijevic, B., Dai, B., Ezashi, T., Livingston, T., Roberts, R.M., and Rasmussen, T.P. (2009) Progressive accumulation of epigenetic heterogeneity during human ES cell culture. Epigenetics 4(5): 330-338. PMID: 19571681

 

  1. Barry, E.R., Krueger, W., Jakuba, C.M., Veilleux, E., Ambrosi, D.J., Nelson, C.E., and Rasmussen, T.P. (2009).The histone methyltransferase Dot1L is required for cell cycle progression and chromosomal stability in differentiating ES cells. Stem Cells, 27(7):1538-1547. PMID: 19544450

 

  1. Godman, C. A., Joshi, R., Tierney, B.R., Greenspan, E., Rasmussen, T.P., Wang, H.W., Shin, D.G., Rosenberg, D.W., and Giardina, C. (2008) HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Biology and Therapy 7(10): 1570-1580. PMID:18769117

 

  1. Rasmussen, T.P., (2008) Developmentally-poised chromatin of embryonic stem cells. Frontiers in Bioscience13, 1568-1577. PMID:17981649

 

  1. Spurling, C.C., Godman, C.A., Noonan, E.J., Rasmussen, T.P., Rosenberg, D.W., and Giardina C. (2008) HDAC3 over-expression and colon cancer cell proliferation and differentiation. Molecular Carcinogenesis47(2): 137-147. PMID: 17849419

 

  1. Dai, B. and Rasmussen, T.P. (2007) Global Epiproteomic Signatures Distinguish ES Cells from Differentiated Cells. Stem Cells, 25(10): 2567-2574. PMID: 17641388

 

  1. Ambrosi, D.J., Tanasijevic, B., Kaur, A. Obergfell, C., O’Neill, R.J., Krueger, W., and Rasmussen, T.P. (2007) Genome-wide reprogramming in hybrids of somatic cells and embryonic stem cells. Stem Cells, 25(5), 1104-1113. PMID: 17272499

 

  1. Ambrosi, D.J. and Rasmussen, T.P. (2005) Reprogramming mediated by stem cell fusion. Journal of Cellular and Molecular Medicine 9, 320-330. PMID: 15963252

 

  1. Chang, C.C., Nagy, Z.P., Kort, H.I., Rasmussen, T.P., Yang, X., Tian, X.C. (2006) Dynamic distribution of heterochromatin protein 1b in preimplantation embryos. Fertility and Sterility, (86) S79-80.

 

  1. Ma, Y.H., Jacobs, S.B., Jackson-Grusby, L., Mastrangelo, M.A., Torres-Betancourt, J.A., Jaenisch, R., and Rasmussen, T.P. (2005). DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. Journal of Cell Science, 118, 1607-1616. PMID:15784683

 

  1. Chang, C.C., Ma, Y.H., Jacobs, S., Tian X.C., Yang, X. , and Rasmussen, T.P. (2005). A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos. Developmental Biology, 278, 367-380.  PMID: 15680357

 

  1. Kim, C., Ma, Y., Chang, C.C., Rasmussen, T.P., Yang, X., and Tian, C. (2005) Distribution of histone macroH2A1 in bovine pre-implantation embryos derived from parthenogenetic activation and in vitro fertilization. Reproduction, Fertility and Development, 18(2) 232 – 233.

 

  1. Rasmussen, T.P. (2003). Embryonic stem cell differentiation: a chromatin perspective. Reproductive Biology and Endocrinology, 1, 100-107. PMID:14614777

 

  1. Ganesan,S., Silver, D.P., Greenberg, R.A., Avni, D., Drapkin, R., Miron, A., Mok, S.C., Randrianarison, R., Brodie, S., Salstrom, J., Rasmussen, T.P., Klimke, A., Marrese, C., Marahrens, Y., Deng, C.X., Feunteun, J. , and Livingston, D.M. (2002). BRCA1 Supports XIST RNA Concentration on the Inactive X Chromosome. Cell, 111, 393-405. PMID: 12419249

 

  1. Wutz, A., Rasmussen, T.P., and Jaenisch, R. (2002). Chromosomal silencing and chromosomal localisation are mediated by different domains of Xist RNA. Nature Genetics, 30, 167-74. PMID: 11780141

 

  1. Rasmussen, T. P., Wutz, A., Pehrson, J. R., and Jaenisch, R. (2001). Expression of Xist RNA is sufficient to initiate macrochromatin body formation. Chromosoma, 110, 411-420. PMID: 11734999

 

  1. Akbarian, S., Chen, R. Z., Gribnau, J., Rasmussen, T. P., Fong, H., Jaenisch, R., and Jones, E. G. (2001). Expression pattern of the Rett Syndrome Gene MeCP2 in primate prefrontal cortex. Neurobiology of Disease, 8, 784-791. PMID:11592848

 

  1. Rasmussen, T. P., Mastrangelo, M. A., Eden, A., Pehrson, J. R., and Jaenisch, R. (2000). Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivation. Journal of Cell Biology, 150, 1189-98. PMID:10974005

 

  1. Rasmussen, T. P., Huang, T., Mastrangelo, M. A., Loring, J., Panning, B., and Jaenisch, R. (1999). Messenger RNAs encoding mouse histone macroH2A1 isoforms are expressed at similar levels in male and female cells and result from alternative splicing. Nucleic Acids Research, 27, 3685-9. PMID:10471737

 

  1. Rasmussen, T. P., and Culbertson, M. R. (1998). The putative nucleic acid helicase Sen1p is required for formation and stability of termini and for maximal rates of synthesis and levels of accumulation of small nucleolar RNAs in Saccharomyces cerevisiae. Molecular and Cellular Biology, 18, 6885-96. PMID: 9819377

 

  1. Rasmussen, T. P., and Culbertson, M. R. (1996). Analysis of yeast trimethylguanosine-capped RNAs by midwestern blotting. Gene, 182, 89-96. PMID: 8982072

 

  1. DeMarini, D. J., Papa, F. R., Swaminathan, S., Ursic, D., Rasmussen, T. P., Culbertson, M. R., and Hochstrasser, M. (1995). The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo. Molecular and Cellular Biology, 15, 6311-21. PMID: 7565784

 

 

Books Edited:

 

  1. 54. Rasmussen, T. (2018) Stem Cells in Birth Defects Research and Developmental Toxicology.Rasmussen ed., John Wiley Publishers, Hoboken, NJ.

 

 

 

Published Book Chapters:

 

 

  1. Rasmussen TP (2019). Pluripotent cells for the assessment of chemically-induced teratogenesis and developmental toxicology: in Engineering Strategies for Regenerative Medicine (Elsevier) (in press)

 

  1. Prabhakar, B., Lee, S., and Rasmussen, T.P. (2018) The basics of stem cells and their utility as platforms to model teratogen action and human developmental and degenerative disorders: in Stem Cells in Birth Defects Research and Developmental Toxicology. Hoboken, N.J.: John Wiley and Sons, Rasmussen ed. (in press).

 

  1. Rasmussen, T.P. (2016) Genomic medicine and lipid metabolism: LDL targets and stem cell research approaches. In: Translational Cardiometabolic Genomic Medicine (New York: Elsevier, Oquendo-Rodriguez ed. (London: Elsevier, 2016).

 

  1. Rasmussen, T. (2015) The epigenetics of nuclear reprogramming. Epigenetics: Current Research and Emerging Trends.: Caister Academic Press, Chadwick ed. (Poole, UK: 2015).

 

  1. Dai, B., Giardina, C., and Rasmussen, T.P. (2012) Quantitation of Nucleosome Acetylation and Other Modifications Using Microscale NU-ELISA. Methods in Molecular Biology. (New York: Humana Press, 2012).

 

Publication Impact Factors:

 

SCOPUS (Elsevier):   h-index = 28

Google Scholar:  h-index = 28

                            i10 index = 37